INT114603

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Context Info
Confidence 0.21
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il10) extracellular region (Il10) intracellular (Il10)
Anatomy Link Frequency
brain 2
Il10 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 1 100.00 Very High Very High Very High
Inflammation 1 100.00 Very High Very High Very High
Inflammatory response 1 96.32 Very High Very High Very High
antagonist 1 91.80 High High
Pain threshold 1 81.44 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 2 100.00 Very High Very High Very High
Anxiety Disorder 4 96.44 Very High Very High Very High
Pain 1 81.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Central administration of IL-1beta significantly increased prostaglandin E2 and decreased the anti-inflammatory cytokine IL-10 release from whole blood cultures; therefore this treatment appears to be effective in inducing an inflammatory response in both the periphery and the brain.
Negative_regulation (decreased) of Localization (release) of cytokine IL-10 in brain associated with inflammatory response, inflammation and cytokine
1) Confidence 0.21 Published 2003 Journal Eur. J. Neurosci. Section Abstract Doc Link 14622208 Disease Relevance 0.61 Pain Relevance 0.28

General Comments

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