INT114608

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Context Info
Confidence 0.27
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Acsl1) endoplasmic reticulum (Acsl1) plasma membrane (Acsl1)
peroxisome (Acsl1) ligase activity (Acsl1) lipid metabolic process (Acsl1)
Anatomy Link Frequency
paw 2
Acsl1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Lasting pain 3 98.32 Very High Very High Very High
Central nervous system 4 96.76 Very High Very High Very High
Hyperalgesia 1 84.08 Quite High
central sensitization 1 82.84 Quite High
Spinal cord 3 77.52 Quite High
Pain 1 76.40 Quite High
Inflammation 6 75.00 Quite High
Sciatic nerve 1 53.60 Quite High
intrathecal 1 47.04 Quite Low
antagonist 1 42.72 Quite Low
Disease Link Frequency Relevance Heat
Pain 3 98.32 Very High Very High Very High
Hyperalgesia 1 84.08 Quite High
INFLAMMATION 3 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using semiquantitative RT-PCR, we explored in the neuraxis the mRNA expression of brain acyl-CoA synthetases (ACS) and acyl-CoA oxidase (ACO), which are major fatty acid-metabolizing enzymes, following complete Freund's adjuvant (CFA) injection into a hind paw.
Negative_regulation (explored) of Transcription (expression) of ACS in paw
1) Confidence 0.27 Published 2003 Journal Eur. J. Neurosci. Section Abstract Doc Link 14622223 Disease Relevance 0.48 Pain Relevance 0.75

General Comments

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