INT114647

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Context Info
Confidence 0.48
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Fos) DNA binding (Fos) response to stress (Fos)
cell death (PDYN) extracellular region (PDYN) nucleolus (Fos)
Anatomy Link Frequency
spinal 2
Fos (Rattus norvegicus)
PDYN (Homo sapiens)
Pain Link Frequency Relevance Heat
Dynorphin 6 100.00 Very High Very High Very High
Brush evoked pain 2 88.40 High High
Thermal hyperalgesia 2 86.64 High High
Hyperalgesia 2 75.00 Quite High
allodynia 1 75.00 Quite High
intrathecal 2 69.92 Quite High
withdrawal 1 58.24 Quite High
Disease Link Frequency Relevance Heat
Nociception 3 100.00 Very High Very High Very High
Neuropathic Pain 3 88.40 High High
Hyperalgesia 4 86.64 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibition of spinal Fos expression increases formalin-induced nociception and decreases spinal prodynorphin messenger ribonucleic acid (mRNA), suggesting that Fos modulates nociception by inducing dynorphin synthesis.
Fos Positive_regulation (inducing) of Gene_expression (synthesis) of dynorphin in spinal associated with nociception and dynorphin
1) Confidence 0.48 Published 2001 Journal J Pain Section Abstract Doc Link 14622822 Disease Relevance 0.52 Pain Relevance 0.52

General Comments

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