INT114676

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Context Info
Confidence 0.10
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Mdm2) intracellular (Mdm2) enzyme binding (Mdm2)
protein complex assembly (Mdm2) protein complex (Mdm2) cytoplasm (Mdm2)
Mdm2 (Rattus norvegicus)
p53-ps (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 3 76.24 Quite High
Thalamus 2 75.20 Quite High
Morphine 6 75.00 Quite High
cocaine 3 75.00 Quite High
amygdala 2 74.40 Quite High
Central grey 1 73.60 Quite High
Locus ceruleus 1 71.68 Quite High
addiction 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Apoptosis 1 98.60 Very High Very High Very High
Neurodegenerative Disease 1 92.56 High High
Urological Neuroanatomy 1 73.60 Quite High
Drug Dependence 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our present study investigated the effects of treatments with different addictive drugs on gene expression of murine double minute clone 2 (MDM2), a key negative regulator of p53 and an important mediator in cell apoptosis.
MDM2 Negative_regulation (regulator) of p53 associated with apoptosis
1) Confidence 0.10 Published 2003 Journal Neurosci. Lett. Section Abstract Doc Link 14625023 Disease Relevance 0.26 Pain Relevance 0.48

General Comments

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