INT114769

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.14
First Reported 2003
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 0.58
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Enpep) peptidase activity (Enpep) plasma membrane (Enpep)
Anatomy Link Frequency
glomerulus 1
Enpep (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 6 100.00 Very High Very High Very High
opiate 2 98.92 Very High Very High Very High
Opioid 1 98.32 Very High Very High Very High
agonist 4 56.08 Quite High
antagonist 10 52.36 Quite High
Central nervous system 4 5.00 Very Low Very Low Very Low
Dismenorea 4 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 58 98.20 Very High Very High Very High
Obesity 2 96.48 Very High Very High Very High
Pre-eclampsia 92 87.76 High High
Pre-term Labor 54 55.32 Quite High
Hypoxia 4 43.00 Quite Low
Cardiovascular Disorder Under Development 2 28.20 Quite Low
Hypertrophy 2 27.24 Quite Low
Aging 4 7.84 Low Low
Snake Bites 24 5.00 Very Low Very Low Very Low
Premature Birth 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus the sequence of rhiminopeptidase A contains the key amino acids required for it to function as a calcium-modulated aminopeptidase A.


Regulation (modulated) of aminopeptidase
1) Confidence 0.14 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2919393 Disease Relevance 0 Pain Relevance 0
We have purified an aminopeptidase A from this venom and shown that it has a relatively broad specificity (APN, APB and APA activities) in the absence of calcium, but a higher and very specific APA activity in the presence of calcium.
Regulation (specificity) of APA
2) Confidence 0.14 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2919393 Disease Relevance 0 Pain Relevance 0
The aim of the present work is to study the influence of orchidectomy and testosterone (T) replacement on soluble (S) and membrane bound (MB) enkephalin-degrading aminopeptidase (EDA) activities in the HPA axis.
Regulation (influence) of enkephalin-degrading aminopeptidase associated with enkephalin
3) Confidence 0.14 Published 2003 Journal Gen. Comp. Endocrinol. Section Abstract Doc Link 14636637 Disease Relevance 0 Pain Relevance 0.27
Our laboratory has measured changes in renal APA activity and histological changes in the glomerulus of both DSS and Dahl salt-resistant (DSR) rats [46].
Regulation (changes) of APA in glomerulus
4) Confidence 0.11 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3005972 Disease Relevance 0.48 Pain Relevance 0.05
The rat homologue of human P-LAP is insulin-regulated aminopeptidase (IRAP) [57].
Regulation (regulated) of aminopeptidase
5) Confidence 0.11 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3005972 Disease Relevance 0.10 Pain Relevance 0
Effects of orchidectomy and testosterone replacement on mouse enkephalin-degrading aminopeptidase activity in the HPA axis.
Regulation (Effects) of enkephalin-degrading aminopeptidase associated with enkephalin
6) Confidence 0.08 Published 2003 Journal Gen. Comp. Endocrinol. Section Title Doc Link 14636637 Disease Relevance 0 Pain Relevance 0.29
Influence of hormonal status on enkephalin-degrading aminopeptidase activity in the HPA axis of female mice.
Regulation (Influence) of enkephalin-degrading aminopeptidase associated with enkephalin
7) Confidence 0.03 Published 2005 Journal Gen. Comp. Endocrinol. Section Title Doc Link 15748714 Disease Relevance 0 Pain Relevance 0.28

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox