INT11477

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Context Info
Confidence 0.01
First Reported 1992
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.98
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

H2-K1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 4 99.10 Very High Very High Very High
bradykinin 6 98.28 Very High Very High Very High
Disease Link Frequency Relevance Heat
Syndrome 2 99.30 Very High Very High Very High
Pain 4 99.10 Very High Very High Very High
Hypersensitivity 4 98.72 Very High Very High Very High
Pox Virus Infection 2 70.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggest that the ameliorating effects of Neurotropin in allergic disorders and pain syndromes may be related to this ability to inhibit activation of the K-K cascade and consequently the formation of BK.
Negative_regulation (inhibit) of Positive_regulation (activation) of K-K associated with pain, syndrome, hypersensitivity and bradykinin
1) Confidence 0.01 Published 1992 Journal Biochem. Pharmacol. Section Abstract Doc Link 1562287 Disease Relevance 0.48 Pain Relevance 0.30
These data suggest that the ameliorating effects of Neurotropin in allergic disorders and pain syndromes may be related to this ability to inhibit activation of the K-K cascade and, consequently, the formation of bradykinin.
Negative_regulation (inhibit) of Positive_regulation (activation) of K-K associated with pain, syndrome, hypersensitivity and bradykinin
2) Confidence 0.01 Published 1998 Journal Biochem. Pharmacol. Section Abstract Doc Link 9719471 Disease Relevance 0.50 Pain Relevance 0.25

General Comments

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