INT114815

Context Info Confidence 0.45 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.68 Pain Relevance 0.47

peptidase activity (Afg3l2) mitochondrion (Afg3l2)

Anatomy Link Frequency peripheral nervous system 1 Afg3l2 (Mus musculus)

Pain Link Frequency Relevance Heat Peripheral nervous system 1 99.56 Inflammation 6 99.52 Hyperalgesia 1 96.68 Pain 1 67.00

Disease Link Frequency Relevance Heat INFLAMMATION 5 99.52 Neurogenic Inflammation 1 97.80 Hyperalgesia 1 96.68 Pain 1 67.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Inflammation is mediated in part by activation of PAR(2) in the peripheral nervous system, which results in neurogenic inflammation and hyperalgesia.

Positive_regulation (activation) of PAR in peripheral nervous system associated with hyperalgesia, peripheral nervous system, inflammation and neurogenic inflammation

1) Confidence 0.45 Published 2003 Journal Biochem. Soc. Trans. Section Abstract Doc Link 14641024 Disease Relevance 0.68 Pain Relevance 0.47

General Comments

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