INT114827

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Context Info
Confidence 0.45
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 13
Total Number 15
Disease Relevance 5.69
Pain Relevance 1.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (Tymp)
Anatomy Link Frequency
bladder 2
Tymp (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 11 99.84 Very High Very High Very High
interstitial cystitis 9 98.00 Very High Very High Very High
agonist 220 97.44 Very High Very High Very High
Crohn's disease 1 84.68 Quite High
Inflammation 3 83.44 Quite High
Fibrositis 1 82.88 Quite High
spastic colon 1 82.32 Quite High
Bile 36 50.00 Quite Low
Angina 11 5.00 Very Low Very Low Very Low
Kinase C 11 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 150 99.72 Very High Very High Very High
Klatskin's Tumor 84 99.56 Very High Very High Very High
Interstitial Cystitis 9 98.00 Very High Very High Very High
Hypersensitivity 15 97.60 Very High Very High Very High
Stress 176 90.64 High High
Ulcers 3 89.84 High High
Biliary Cancer 60 89.60 High High
Syndrome 4 87.80 High High
Systemic Lupus Erythematosus 1 86.84 High High
Inflammatory Bowel Disease 2 85.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, the sensitivity of tumor cells to capecitabine might be enhanced by increasing TP expression [3,16].
Positive_regulation (increasing) of Gene_expression (expression) of TP associated with cancer
1) Confidence 0.45 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2974735 Disease Relevance 1.05 Pain Relevance 0
In comparison, TP expression was significantly higher in GB cancer than in BDC (p = 0.006).
Positive_regulation (higher) of Gene_expression (expression) of TP associated with klatskin's tumor and cancer
2) Confidence 0.35 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2974735 Disease Relevance 1.05 Pain Relevance 0
However, TP expression was significantly higher in GB cancer than in BDC.
Positive_regulation (higher) of Gene_expression (expression) of TP associated with klatskin's tumor and cancer
3) Confidence 0.35 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2974735 Disease Relevance 1.20 Pain Relevance 0
Addition of H2O2 was found to lead to an increase in detectable surface TP?
Positive_regulation (increase) of Gene_expression (detectable) of TP
4) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939892 Disease Relevance 0 Pain Relevance 0.04
PC3 cells express a large intracellular pool of thromboxane receptor and both the TP?
Positive_regulation (pool) of Gene_expression (express) of TP
5) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939892 Disease Relevance 0 Pain Relevance 0
Next we considered intracellular transport and turnover of TP?
Positive_regulation (turnover) of Gene_expression (turnover) of TP
6) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939892 Disease Relevance 0.06 Pain Relevance 0
, cultures were transfected with ScaI linearized pcDNA3.1-HA-TP?
Positive_regulation (transfected) of Gene_expression (transfected) of TP
7) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939892 Disease Relevance 0 Pain Relevance 0
Cell surface expression of TP?
Positive_regulation (surface) of Gene_expression (expression) of TP
8) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939892 Disease Relevance 0 Pain Relevance 0
Preincubation of non-transfected HEK293 cells with the TP?
Positive_regulation (transfected) of Gene_expression (transfected) of TP
9) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939892 Disease Relevance 0 Pain Relevance 0.17
As this increase is significantly greater than that observed in the absence of lactacystin these data suggest that the proteasome contributes to turnover of TP?
Positive_regulation (turnover) of Gene_expression (turnover) of TP
10) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939892 Disease Relevance 0 Pain Relevance 0
As this increase is significantly greater than that observed in the absence of lactacystin these data suggest that the proteasome contributes to turnover of TP?
Positive_regulation (contributes) of Gene_expression (turnover) of TP
11) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939892 Disease Relevance 0 Pain Relevance 0
An increased expression of certain growth factors (PD-ECGF, FGF, and VEGF) has been found in the bladder of IC patients.
Positive_regulation (ncreased ) of Gene_expression (xpression ) of PD-ECGF in bladder associated with interstitial cystitis
12) Confidence 0.05 Published 2003 Journal Int. J. Urol. Section Abstract Doc Link 14641413 Disease Relevance 2.24 Pain Relevance 0.90
In the absence of brefeldin A, and consistent with our previous studies, H2O2 induced increased expression of HA-TP?
Positive_regulation (increased) of Gene_expression (expression) of TP
13) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939892 Disease Relevance 0 Pain Relevance 0
Quantification of the FITC-fluorescence intensity associated with the increased surface expression of TP?
Positive_regulation (increased) of Gene_expression (expression) of TP
14) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939892 Disease Relevance 0.09 Pain Relevance 0
In the absence of brefeldin A, and consistent with our previous studies, H2O2 induced increased expression of HA-TP?
Positive_regulation (induced) of Gene_expression (expression) of TP
15) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939892 Disease Relevance 0 Pain Relevance 0

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