INT114838

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Context Info
Confidence 0.54
First Reported 2003
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.89
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Lgals1) cytoplasm (Lgals1) signal transducer activity (Lgals1)
extracellular space (Lgals1) signal transduction (Lgals1) extracellular region (Lgals1)
Anatomy Link Frequency
PSCs 1
dorsal horn 1
Lgals1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
chemokine 5 99.84 Very High Very High Very High
Dorsal horn 3 99.68 Very High Very High Very High
intrathecal 1 95.92 Very High Very High Very High
dorsal root ganglion 6 95.12 Very High Very High Very High
Spinal cord 2 90.56 High High
substance P 1 83.92 Quite High
cytokine 1 82.40 Quite High
spinal dorsal horn 1 81.20 Quite High
Peripheral nerve injury 2 75.60 Quite High
Neuropathic pain 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 6 95.12 Very High Very High Very High
Hypersensitivity 1 78.16 Quite High
Apoptosis 1 76.64 Quite High
Neuropathic Pain 2 75.00 Quite High
Nervous System Injury 2 74.72 Quite High
Pancreatic Cancer 1 49.44 Quite Low
Pancreatitis 1 46.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Galectin-1-IR was increased in the dorsal horn at 1 to 2 weeks after axotomy.
Positive_regulation (increased) of Galectin-1-IR in dorsal horn associated with dorsal horn
1) Confidence 0.54 Published 2003 Journal Brain Res. Section Abstract Doc Link 14642832 Disease Relevance 0.89 Pain Relevance 0.81
In conclusion, our results suggest a role of galectin-1 in chemokine production and proliferation through its beta-galactoside binding activity in activated PSCs.
Positive_regulation (role) of galectin-1 in PSCs associated with chemokine
2) Confidence 0.47 Published 2006 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 16373424 Disease Relevance 0 Pain Relevance 0.21

General Comments

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