INT114844

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Context Info
Confidence 0.16
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.95
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Lgals1, TACR1) signal transducer activity (Lgals1, TACR1) intracellular (Lgals1)
extracellular space (Lgals1) signal transduction (Lgals1) extracellular region (Lgals1)
Anatomy Link Frequency
dorsal horn 1
Lgals1 (Rattus norvegicus)
TACR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Peripheral nerve injury 2 100.00 Very High Very High Very High
Neuropathic pain 2 100.00 Very High Very High Very High
Dorsal horn 3 99.68 Very High Very High Very High
spinal dorsal horn 1 95.52 Very High Very High Very High
substance P 1 93.88 High High
intrathecal 1 87.88 High High
dorsal root ganglion 6 79.44 Quite High
Spinal cord 2 74.88 Quite High
Pain 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 2 100.00 Very High Very High Very High
Nervous System Injury 2 100.00 Very High Very High Very High
Hypersensitivity 1 96.96 Very High Very High Very High
Ganglion Cysts 6 79.44 Quite High
Apoptosis 1 60.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggest that endogenous galectin-1 may potentiate neuropathic pain after the peripheral nerve injury at least partly by increasing SPR in the dorsal horn.
galectin-1 Positive_regulation (increasing) of SPR in dorsal horn associated with nervous system injury, dorsal horn, neuropathic pain and peripheral nerve injury
1) Confidence 0.16 Published 2003 Journal Brain Res. Section Abstract Doc Link 14642832 Disease Relevance 0.95 Pain Relevance 0.82

General Comments

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