INT114948

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Context Info
Confidence 0.20
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NCOA1, PPARA) small molecule metabolic process (NCOA1, PPARA) DNA binding (NCOA1, PPARA)
nucleus (NCOA1, PPARA) enzyme binding (NCOA1) transferase activity, transferring acyl groups (NCOA1)
NCOA1 (Homo sapiens)
PPARA (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 100.00 Very High Very High Very High
cINOD 7 85.36 High High
antagonist 3 74.48 Quite High
diclofenac 1 41.68 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 3 84.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that co-expression of PPAR delta, retinoid X receptor (RXR) alpha, and coactivators such as CBP and SRC-1 enhanced basal and agonist-dependent activation of PPAR responsive element (PPRE)-driven transcription by PPAR delta, rendering a PPRE-driven reporter assay reliable and sensitive.
SRC-1 Positive_regulation (enhanced) of Positive_regulation (activation) of PPAR associated with agonist
1) Confidence 0.20 Published 2003 Journal J. Pharmacol. Sci. Section Abstract Doc Link 14646253 Disease Relevance 0.24 Pain Relevance 0.62

General Comments

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