INT114958

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Context Info
Confidence 0.41
First Reported 2002
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.24
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NCOA1) small molecule metabolic process (NCOA1) nucleus (NCOA1)
enzyme binding (NCOA1) transferase activity, transferring acyl groups (NCOA1) DNA binding (NCOA1)
NCOA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 7 99.20 Very High Very High Very High
cINOD 7 89.16 High High
antagonist 5 70.00 Quite High
diclofenac 1 37.20 Quite Low
Potency 3 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 88.60 High High
Reprotox - General 1 1 49.52 Quite Low
Hypersensitivity 6 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Adenocarcinoma 1 5.00 Very Low Very Low Very Low
Wrinkles 1 5.00 Very Low Very Low Very Low
Charcot Marie Tooth Disease 1 5.00 Very Low Very Low Very Low
Acute Promyelocytic Leukemia 1 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We then assayed similarly expression levels for nuclear coactivators AIB1 [16], CBP [17], p300 [18], p/CIP [19], RAC3 [20], RIP140 [21], SRC1 [22], TIF1 [23], TIF2 [24] and TRIP1 [25].
Gene_expression (expression) of SRC1
1) Confidence 0.41 Published 2002 Journal BMC Pharmacol Section Body Doc Link PMC113761 Disease Relevance 0 Pain Relevance 0
We found that co-expression of PPAR delta, retinoid X receptor (RXR) alpha, and coactivators such as CBP and SRC-1 enhanced basal and agonist-dependent activation of PPAR responsive element (PPRE)-driven transcription by PPAR delta, rendering a PPRE-driven reporter assay reliable and sensitive.
Gene_expression (co-expression) of SRC-1 associated with agonist
2) Confidence 0.25 Published 2003 Journal J. Pharmacol. Sci. Section Abstract Doc Link 14646253 Disease Relevance 0.24 Pain Relevance 0.60

General Comments

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