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Context Info
Confidence 0.50
First Reported 2003
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.06
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RXRA) small molecule metabolic process (RXRA) aging (RXRA)
nucleus (RXRA) enzyme binding (RXRA) DNA binding (RXRA)
RXRA (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 4 97.12 Very High Very High Very High
cINOD 9 89.04 High High
Inflammation 3 66.48 Quite High
antagonist 3 65.84 Quite High
cytokine 1 65.44 Quite High
diclofenac 1 33.04 Quite Low
Disease Link Frequency Relevance Heat
Colon Cancer 42 98.68 Very High Very High Very High
Apoptosis 3 89.84 High High
INFLAMMATION 7 88.48 High High
Rheumatoid Arthritis 2 77.20 Quite High
Cancer 44 60.00 Quite High
Metabolic Disorder 6 52.16 Quite High
Body Weight 1 50.00 Quite Low
Polyps 4 37.52 Quite Low
Diabetes Mellitus 4 19.08 Low Low
Obesity 35 16.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that co-expression of PPAR delta, retinoid X receptor (RXR) alpha, and coactivators such as CBP and SRC-1 enhanced basal and agonist-dependent activation of PPAR responsive element (PPRE)-driven transcription by PPAR delta, rendering a PPRE-driven reporter assay reliable and sensitive.
Gene_expression (expression) of retinoid X receptor associated with agonist
1) Confidence 0.50 Published 2003 Journal J. Pharmacol. Sci. Section Abstract Doc Link 14646253 Disease Relevance 0.24 Pain Relevance 0.54
Alterations in retinoid-activated receptor expression and biological activity have been observed both in vivo and in vitro [28].
Gene_expression (expression) of retinoid-activated receptor
2) Confidence 0.02 Published 2007 Journal Nutr J Section Body Doc Link PMC2018695 Disease Relevance 0.82 Pain Relevance 0.09

General Comments

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