INT115003

Context Info Confidence 0.28 First Reported 2003 Last Reported 2006 Negated 0 Speculated 0 Reported most in Abstract Documents 2 Total Number 2 Disease Relevance 0.47 Pain Relevance 0.19

mitochondrion (Msra) oxidoreductase activity (Msra) aging (Msra) nucleus (Msra) cytoplasm (Msra)

Anatomy Link Frequency liver 1 Msra (Mus musculus)

Pain Link Frequency Relevance Heat cINOD 2 76.92 Inflammation 3 70.28 tolerance 3 5.00 Paracetamol 1 5.00 cerebral cortex 1 5.00 withdrawal 1 5.00 ischemia 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 4 83.96 Cancer 17 82.72 Colon Cancer 1 79.48 INFLAMMATION 4 76.40 Stress 93 50.00 Aging 37 50.00 Shock 7 40.32 Lifespan 22 28.80 Targeted Disruption 35 5.00 Death 5 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Preliminary studies indicate that the combined activities of MsrA and MsrB (measured as total Msr activity) of dwarf liver are not different from the wild-type animals, perhaps reflecting the varying protein levels.

MsrA Binding (activities) of in liver

1) Confidence 0.28 Published 2006 Journal Age (Dordr) Section Body Doc Link PMC2464727 Disease Relevance 0 Pain Relevance 0

Only MsrA and a membrane associated Msr can reduce sulindac to the active sulfide.

Msr Binding (associated) of

2) Confidence 0.08 Published 2003 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 14651971 Disease Relevance 0.47 Pain Relevance 0.19

General Comments

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