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Context Info
Confidence 0.66
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.14
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Tlx2) DNA binding (Tlx2) cytoplasm (Tlx2)
Anatomy Link Frequency
spinal cord dorsal columns 1
Tlx2 (Mus musculus)
Pain Link Frequency Relevance Heat
sodium channel 5 95.64 Very High Very High Very High
Spinal cord 3 90.32 High High
Multiple sclerosis 2 75.32 Quite High
Nav1.6 1 75.00 Quite High
imagery 13 57.28 Quite High
aspirin 13 50.00 Quite Low
cINOD 4 27.20 Quite Low
Inflammation 1 25.04 Quite Low
tolerance 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 67 99.00 Very High Very High Very High
Multiple Sclerosis 7 98.56 Very High Very High Very High
Experimental Autoimmune Encephalomyelitis 1 98.36 Very High Very High Very High
Ovarian Cancer 33 98.24 Very High Very High Very High
Injury 5 96.92 Very High Very High Very High
Alzheimer's Dementia 1 93.20 High High
Apoptosis 10 91.44 High High
Liver Cancer 1 90.00 High High
Hyperplasia 1 65.12 Quite High
Skin Cancer 1 34.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Based on the hypothesis that the co-localization of Na(v)1.6 and NCX along extensive regions of demyelinated axons may predispose these axons to injury, we examined the expression of myelin basic protein, Na(v)1.2, Na(v)1.6, NCX and beta-amyloid precursor protein (beta-APP), a marker of axonal injury, in the spinal cord dorsal columns of mice with EAE.
Localization (co-localization) of NCX in spinal cord dorsal columns associated with multiple sclerosis, alzheimer's dementia, injury and spinal cord
1) Confidence 0.66 Published 2004 Journal Brain Section Abstract Doc Link 14662515 Disease Relevance 1.01 Pain Relevance 0.44
NCX-4040 is capable of releasing nitric oxide and depleting thiols in human ovarian cancer cells.
Localization (releasing) of NCX-4040 associated with ovarian cancer
2) Confidence 0.03 Published 2008 Journal J Transl Med Section Body Doc Link PMC2267444 Disease Relevance 1.13 Pain Relevance 0.06

General Comments

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