INT115156

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Context Info
Confidence 0.25
First Reported 2004
Last Reported 2005
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.86
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PPARG) enzyme binding (PPARG) DNA binding (PPARG)
lipid metabolic process (PPARG) cytoplasm (PPARG) cytosol (PPARG)
Anatomy Link Frequency
neurons 2
PPARG (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 2 90.16 High High
cINOD 6 88.16 High High
agonist 1 44.96 Quite Low
cytokine 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 5 99.22 Very High Very High Very High
Apoptosis 4 82.44 Quite High
Retinoblastoma 2 75.00 Quite High
Disease 1 75.00 Quite High
INFLAMMATION 2 70.40 Quite High
Colon Cancer 1 41.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results suggest that EGR-1 induction is a unique property of TGZ, but is independent of PPARgamma activation.
Neg (independent) Regulation (independent) of Positive_regulation (activation) of PPARgamma
1) Confidence 0.25 Published 2004 Journal J. Biol. Chem. Section Abstract Doc Link 14662774 Disease Relevance 0.13 Pain Relevance 0.15
Since cell cycle dysfunction is not restricted to neurons in AD, we found it interesting to study the role of PPARgamma activation on cell proliferation in immortalized lymphocytes from AD patients.
Regulation (role) of Positive_regulation (activation) of PPARgamma in neurons associated with alzheimer's dementia
2) Confidence 0.13 Published 2005 Journal Exp. Neurol. Section Abstract Doc Link 16061222 Disease Relevance 0.73 Pain Relevance 0.39

General Comments

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