INT115192

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Context Info
Confidence 0.70
First Reported 2003
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 1.55
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6) aging (IL6) extracellular region (IL6)
Anatomy Link Frequency
muscle 1
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 229 99.36 Very High Very High Very High
Paracetamol 6 93.52 High High
adenocard 1 78.88 Quite High
Inflammation 111 67.44 Quite High
Inflammatory mediators 27 5.00 Very Low Very Low Very Low
Arthritis 11 5.00 Very Low Very Low Very Low
Inflammatory response 10 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperlipoproteinemia Type Ii 5 92.52 High High
Adhesions 7 75.00 Quite High
Death 8 69.60 Quite High
INFLAMMATION 152 67.44 Quite High
Hypertrophy 10 66.68 Quite High
Injury 21 60.96 Quite High
Carcinoma 49 59.36 Quite High
Cancer 40 58.80 Quite High
Cleidocranial Dysplasia 12 58.80 Quite High
Metaplasia 24 58.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Bisphosphonates and Interleukin 6
Phosphorylation (Bisphosphonates) of Interleukin 6
1) Confidence 0.70 Published 2007 Journal Immun Ageing Section Body Doc Link PMC1845171 Disease Relevance 0.66 Pain Relevance 0.04
Immunohistochemical analysis of muscle cross-sections was performed for the quantification of SCs (Pax7+ cells) as well as the expression of phosphorylated STAT3, IL-6, IL-6R?
Phosphorylation (phosphorylated) of IL-6 in muscle
2) Confidence 0.60 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2696599 Disease Relevance 0.13 Pain Relevance 0.04
STAT3 phosphorylation by OSM and IL-6, and STAT1 phosphorylation by OSM, IL-6 and IFN?
Phosphorylation (phosphorylation) of IL-6
3) Confidence 0.40 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1289280 Disease Relevance 0.23 Pain Relevance 0.03
STAT3 phosphorylation by OSM and IL-6, and STAT1 phosphorylation by OSM, IL-6 and IFN?
Phosphorylation (phosphorylation) of IL-6
4) Confidence 0.40 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1289280 Disease Relevance 0.23 Pain Relevance 0.03
STAT3 phosphorylation by OSM and IL-6, and STAT1 phosphorylation by OSM, IL-6 and IFN?
Phosphorylation (phosphorylation) of IL-6
5) Confidence 0.40 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1289280 Disease Relevance 0.23 Pain Relevance 0.06
In the same cell type neither IL-1beta-dependent SAPK activation nor IL-6-induced STAT3 phosphorylation is affected by the drug.
Phosphorylation (phosphorylation) of IL-6-induced
6) Confidence 0.10 Published 2003 Journal Neurosci. Lett. Section Abstract Doc Link 14664905 Disease Relevance 0 Pain Relevance 0.48
The concentration of IL-2, IL-4, IL-6, IL-10, TNF-?
Phosphorylation (concentration) of IL-6
7) Confidence 0.08 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2374764 Disease Relevance 0.07 Pain Relevance 0.16

General Comments

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