INT115214

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.63
First Reported 2004
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 7
Disease Relevance 2.50
Pain Relevance 1.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (LSAMP) plasma membrane (LSAMP)
Anatomy Link Frequency
nervous system 1
LSAMP (Homo sapiens)
Pain Link Frequency Relevance Heat
Limbic system 2 100.00 Very High Very High Very High
substance P 6 99.88 Very High Very High Very High
Enkephalin 8 99.00 Very High Very High Very High
Opioid 2 98.70 Very High Very High Very High
Thalamus 2 91.96 High High
Angina 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 9 100.00 Very High Very High Very High
Nasopharynx Cancer 23 90.84 High High
Ovarian Cancer 4 83.04 Quite High
Disease 36 80.52 Quite High
Cancer 56 77.52 Quite High
Lymphatic Filariasis 20 74.00 Quite High
Infection 29 71.60 Quite High
Viral Meningitis 4 70.08 Quite High
Dengue 4 69.16 Quite High
Malaria 4 68.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One of the in silico identified genes is OPCML (opioid binding protein/cell adhesion molecule-like gene), also known as OBCAM (opioid binding cell adhesion molecule), belonging to the IgLON (OPCML, LSAMP, NEGR1 and HNT) family of glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules that are highly expressed in the nervous system [15]–[18] and involved in cell adhesion and cell-cell recognition [19].
Gene_expression (expressed) of LSAMP in nervous system associated with opioid and adhesions
1) Confidence 0.63 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2500176 Disease Relevance 1.56 Pain Relevance 0.20
In the present study, we carried out histochemical and immunohistochemical procedures in the Pa of normal individuals to visualize the pattern of distribution of acetylcholinesterase (AChE), calbindin D-28k (CB), parvalbumin (PV), calretinin (CR), limbic system-associated membrane protein (LAMP), substance P (SP), and enkephalin (ENK).
Gene_expression (distribution) of limbic system-associated membrane protein associated with enkephalin, limbic system and substance p
2) Confidence 0.55 Published 2004 Journal Synapse Section Abstract Doc Link 14666515 Disease Relevance 0 Pain Relevance 0.47
In the present study, we carried out histochemical and immunohistochemical procedures in the Pa of normal individuals to visualize the pattern of distribution of acetylcholinesterase (AChE), calbindin D-28k (CB), parvalbumin (PV), calretinin (CR), limbic system-associated membrane protein (LAMP), substance P (SP), and enkephalin (ENK).
Gene_expression (distribution) of LAMP associated with enkephalin, limbic system and substance p
3) Confidence 0.55 Published 2004 Journal Synapse Section Abstract Doc Link 14666515 Disease Relevance 0 Pain Relevance 0.47
Furthermore, sequencing of LAMP products showed specific amplification of D. immitis DNA, indicating the high specificity of this method.
Gene_expression (products) of LAMP
4) Confidence 0.06 Published 2009 Journal Parasit Vectors Section Body Doc Link PMC2670822 Disease Relevance 0.82 Pain Relevance 0
LAMP reactions
Gene_expression (reactions) of LAMP
5) Confidence 0.06 Published 2009 Journal Parasit Vectors Section Body Doc Link PMC2670822 Disease Relevance 0.06 Pain Relevance 0
Specific primers for LAMP reactions were designed against the D. immitis cytochrome oxidase subunit I gene (GenBank: EU169124).
Gene_expression (reactions) of LAMP
6) Confidence 0.06 Published 2009 Journal Parasit Vectors Section Body Doc Link PMC2670822 Disease Relevance 0.06 Pain Relevance 0
The LAMP reaction was performed as per manufacture's instructions (Eiken Chemical Co., Ltd., Tokyo, Japan).
Gene_expression (reaction) of LAMP
7) Confidence 0.06 Published 2009 Journal Parasit Vectors Section Body Doc Link PMC2670822 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox