INT115258

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Context Info
Confidence 0.19
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Insr, Irs1) plasma membrane (Insr, Irs1) nucleus (Insr, Irs1)
endosome (Insr) cytoplasm (Irs1) signal transducer activity (Irs1)
Anatomy Link Frequency
skeletal muscle 2
Insr (Rattus norvegicus)
Irs1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 1 80.40 Quite High
Disease Link Frequency Relevance Heat
Obesity 2 86.96 High High
Hyperinsulinism 1 86.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Compared with NS ats, LS ats showed reduced (P < 0.01) basal and insulin-stimulated tyrosine phosphorylation of IRS-1 in skeletal muscle and IRS-2 in live, whereas HS ats showed enhanced basal tyrosine phosphorylation of IRS-1 in skeletal muscle (P < 0.05) and of IRS-2 in live.
insulin Positive_regulation (stimulated) of Phosphorylation (phosphorylation) of IRS-1 in skeletal muscle
1) Confidence 0.19 Published 2004 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 14670806 Disease Relevance 0.26 Pain Relevance 0.08

General Comments

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