INT115329

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Context Info
Confidence 0.38
First Reported 2004
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.67
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (HM13) endoplasmic reticulum (HM13) plasma membrane (HM13)
Anatomy Link Frequency
plasma 1
HM13 (Homo sapiens)
Pain Link Frequency Relevance Heat
headache 1 81.60 Quite High
antagonist 9 78.64 Quite High
Inflammation 60 50.00 Quite Low
Neurotransmitter 5 41.68 Quite Low
Central nervous system 2 21.52 Low Low
cytokine 92 5.00 Very Low Very Low Very Low
Inflammatory response 16 5.00 Very Low Very Low Very Low
sodium channel 10 5.00 Very Low Very Low Very Low
potassium channel 6 5.00 Very Low Very Low Very Low
Catecholamine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bites And Stings 16 85.76 High High
Headache 1 81.60 Quite High
Vomiting 6 80.80 Quite High
Dizziness 1 79.12 Quite High
Pressure Volume 2 Under Development 3 77.92 Quite High
INFLAMMATION 78 50.00 Quite Low
Mydriatic 1 30.96 Quite Low
Ocular Toxicity (including Many Sub-types) 1 30.08 Quite Low
Sialorrhea 1 29.20 Quite Low
Dysphagia 1 27.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At regular intervals, blood pressure and pulse rate, plasma levels of ET-1 and of SPP301 and its hydroxymethyl metabolite, and urinary excretion of the parent drug and its metabolite were determined.
Spec (determined) Gene_expression (levels) of SPP301 in plasma
1) Confidence 0.38 Published 2004 Journal J Clin Pharmacol Section Abstract Doc Link 14681342 Disease Relevance 0.40 Pain Relevance 0.16
Centruroides spp are located in Southwest of United States, Mexico, and Central America, while Tityus spp are found in Central and South America and Caribbean.
Gene_expression (found) of Tityus spp
2) Confidence 0.01 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2838227 Disease Relevance 0.27 Pain Relevance 0

General Comments

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