INT115357

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Context Info
Confidence 0.01
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.55
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (ATP8A1) plasma membrane (ATP8A1) transmembrane transport (ATP8A1)
Anatomy Link Frequency
reticulum 1
ATP8A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal inflammation 1 68.12 Quite High
Inflammation 1 66.44 Quite High
Disease Link Frequency Relevance Heat
Disease 2 100.00 Very High Very High Very High
Thymoma 1 90.68 High High
Arthropathy 1 69.40 Quite High
Low Back Pain 1 68.12 Quite High
Arthritis 1 66.84 Quite High
INFLAMMATION 1 66.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also show that homodimer formation can be induced in the non-disease-associated HLA class I allele HLA-A2 by slowing its assembly rate by incubation of cells at 26 degrees C, suggesting that homodimer formation in the endoplasmic reticulum may occur as a result of the slower folding kinetics of HLA-B27.
Positive_regulation (induced) of class I in reticulum associated with disease
1) Confidence 0.01 Published 2004 Journal J. Biol. Chem. Section Abstract Doc Link 14684742 Disease Relevance 0.55 Pain Relevance 0.10

General Comments

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