INT11551

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.65
First Reported 1992
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 12
Total Number 14
Disease Relevance 22.76
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (VHL) mitochondrion (VHL) cell morphogenesis (VHL)
endoplasmic reticulum (VHL) nucleus (VHL) extracellular matrix organization (VHL)
Anatomy Link Frequency
neck 1
retina 1
medulla 1
germline 1
head 1
VHL (Homo sapiens)
Pain Link Frequency Relevance Heat
medulla 8 97.84 Very High Very High Very High
Angina 1 90.44 High High
Inflammation 1 72.88 Quite High
Morphine 3 70.64 Quite High
anesthesia 11 58.48 Quite High
Catecholamine 65 56.16 Quite High
Spinal cord 4 53.24 Quite High
imagery 49 52.08 Quite High
isoflurane 3 48.72 Quite Low
Versed 3 45.72 Quite Low
Disease Link Frequency Relevance Heat
Syndrome 377 100.00 Very High Very High Very High
Disease 301 100.00 Very High Very High Very High
Hypercalcemia 2 99.94 Very High Very High Very High
Cancer 295 99.92 Very High Very High Very High
Brain Tumor 2 99.92 Very High Very High Very High
Thyroid Neoplasm 2 99.52 Very High Very High Very High
Pancreatic Cancer 5 98.84 Very High Very High Very High
Spermatocele 8 98.30 Very High Very High Very High
Hemangioma 11 98.24 Very High Very High Very High
Polycystic Kidney Disease 8 97.88 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
genotype-phenotype correlations are emerging for VHL disease that relate to the
Localization (disease) of VHL associated with disease
1) Confidence 0.65 Published 2008 Journal Advances in Urology Section Body Doc Link PMC2581790 Disease Relevance 0.63 Pain Relevance 0
or clear cell RCC, who have no detectable VHL disease-causing germline mutation; somatic mosaicism for a VHL gene mutation still needs to be considered in
Localization (disease) of VHL in germline associated with disease
2) Confidence 0.65 Published 2008 Journal Advances in Urology Section Body Doc Link PMC2581790 Disease Relevance 1.11 Pain Relevance 0
A positive test result signals the presence of a VHL disease-causing
Localization (disease) of VHL associated with disease
3) Confidence 0.65 Published 2008 Journal Advances in Urology Section Body Doc Link PMC2581790 Disease Relevance 0.59 Pain Relevance 0
Targeted genetic testing should be proposed to patients with phenotypic clues and/or familial history for MEN-2 (medullary thyroid cancer, hyperparathyroidism), VHL disease (hemangioblastoma, renal or pancreatic tumors), or hereditary PGL (head and neck PGL, familial history in the paternal branch).
Localization (disease) of VHL in neck associated with thyroid neoplasm, pancreatic cancer, paraganglioma, hypercalcemia, disease and brain tumor
4) Confidence 0.63 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1702343 Disease Relevance 2.48 Pain Relevance 0.03
When there is plenty of oxygen, another protein, called von Hippel–Lindau tumor suppressor (abbreviated VHL), rapidly destroys HIF.
Localization (abbreviated) of VHL associated with cancer
5) Confidence 0.63 Published 2006 Journal PLoS Medicine Section Abstract Doc Link PMC1479389 Disease Relevance 0.78 Pain Relevance 0
Renal cysts and epididymal cysts often occur in the normal population and can not be regarded as pathognomonical for VHL disease.
Localization (disease) of VHL associated with spermatocele, syndrome, polycystic kidney disease and disease
6) Confidence 0.62 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC2169240 Disease Relevance 2.66 Pain Relevance 0
Typical tumours in VHL disease are haemangioblastomas of the retina, cerebellum and medulla, renal cell carcinomas (RCC), and pheochromocytomas.
Localization (disease) of VHL in medulla associated with medulla, syndrome, cancer, renal cancer, disease and pheochromocytoma
7) Confidence 0.62 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC2169240 Disease Relevance 3.49 Pain Relevance 0.10
Intracoronary injection of urokinase was not effective for recanalization of RCA.
Localization (recanalization) of RCA in RCA
8) Confidence 0.51 Published 1992 Journal Kokyu To Junkan Section Abstract Doc Link 1570431 Disease Relevance 0.85 Pain Relevance 0.13
Targeted genetic testing should be proposed to patients with phenotypic clues and/or familial history for MEN-2 (medullary thyroid cancer, hyperparathyroidism), VHL disease (hemangioblastoma, renal or pancreatic tumors), or hereditary PGL (head and neck PGL, familial history in the paternal branch).
Localization (disease) of VHL in head associated with thyroid neoplasm, pancreatic cancer, paraganglioma, hypercalcemia, disease and brain tumor
9) Confidence 0.22 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1702343 Disease Relevance 2.48 Pain Relevance 0.03
Typical tumours in VHL disease are haemangioblastomas of the retina, cerebellum and medulla, renal cell carcinomas (RCC), and pheochromocytomas.
Localization (disease) of VHL in cerebellum associated with medulla, syndrome, cancer, renal cancer, disease and pheochromocytoma
10) Confidence 0.21 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC2169240 Disease Relevance 3.49 Pain Relevance 0.10
Typical tumours in VHL disease are haemangioblastomas of the retina, cerebellum and medulla, renal cell carcinomas (RCC), and pheochromocytomas.
Localization (disease) of VHL in retina associated with medulla, syndrome, cancer, renal cancer, disease and pheochromocytoma
11) Confidence 0.21 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC2169240 Disease Relevance 3.49 Pain Relevance 0.10
RCA grafting was performed either at the mid or distal RCA in this study.
Localization (grafting) of RCA
12) Confidence 0.17 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526513 Disease Relevance 0.21 Pain Relevance 0.06
The patients were randomized to RCA revascularization either with intracoronary shunt (Shunt Flo-Thru®, Synovis Surgical Innovations, St.
Localization (revascularization) of RCA
13) Confidence 0.17 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526513 Disease Relevance 0.28 Pain Relevance 0.07
RCA grafting was performed either at the mid or distal RCA in this study.
Localization (grafting) of RCA
14) Confidence 0.17 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526513 Disease Relevance 0.21 Pain Relevance 0.06

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox