INT115517

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.48
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (PRSS2) extracellular space (PRSS2) extracellular region (PRSS2)
PRSS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 4 97.80 Very High Very High Very High
Disease Link Frequency Relevance Heat
Pancreatitis 16 98.56 Very High Very High Very High
Disease 2 82.64 Quite High
Autolysis 2 78.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The observations not only suggest a novel mechanism of action for pancreatitis-associated trypsinogen mutations, but also highlight the importance of interactions between the two major trypsinogen isoforms in the development of genetically determined chronic pancreatitis.
trypsinogen Binding (interactions) of associated with pancreatitis and chronic pancreatitis
1) Confidence 0.48 Published 2004 Journal Hum. Mutat. Section Abstract Doc Link 14695529 Disease Relevance 0.70 Pain Relevance 0.10
Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2).
trypsinogen Binding (Interaction) of associated with pancreatitis
2) Confidence 0.37 Published 2004 Journal Hum. Mutat. Section Title Doc Link 14695529 Disease Relevance 0.38 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox