INT115520

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Context Info
Confidence 0.01
First Reported 2002
Last Reported 2004
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.46
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Itga2) extracellular space (Itga2) cell adhesion (Itga2)
plasma membrane (Itga2) nucleus (Itga2)
Itga2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dexamethasone 14 77.76 Quite High
Inflammatory response 4 50.00 Quite Low
Opioid 4 50.00 Quite Low
IPN 2 50.00 Quite Low
Inflammation 15 10.00 Low Low
Pain 2 10.00 Low Low
chemokine 1 10.00 Low Low
halothane 6 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 5 95.88 Very High Very High Very High
Urological Neuroanatomy 7 79.84 Quite High
INFLAMMATION 18 70.60 Quite High
Inflammatory Pain 2 50.00 Quite Low
Hypersensitivity 12 37.88 Quite Low
Anaphylaxis 28 8.68 Low Low
Food Hypersensitivity 7 5.00 Very Low Very Low Very Low
Coronary Heart Disease 2 5.00 Very Low Very Low Very Low
Diarrhoea 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CD49d was not modified by sensitization or antigen challenge, but feG treatment significantly reduced the expression of this adhesion molecule in OA-exposed animals to values that were 50% of those measured in rats receiving antigen only.


Neg (not) Regulation (modified) of CD49d associated with adhesions
1) Confidence 0.01 Published 2002 Journal BMC Physiol Section Body Doc Link PMC126222 Disease Relevance 0.39 Pain Relevance 0.10
Mobilized PMN had decreased content of beta-endorphin but not of Met-enkephalin per cell, down-regulation of CD62L, up-regulation of CD49d (but no change in CD18), and reduced migration toward higher chemokine concentrations (all P < 0.05).
Regulation (regulation) of CD49d
2) Confidence 0.01 Published 2004 Journal Anesthesiology Section Body Doc Link 14695736 Disease Relevance 0.07 Pain Relevance 0

General Comments

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