INT115663

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Context Info
Confidence 0.44
First Reported 2004
Last Reported 2005
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.20
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ABCB6) mitochondrion (ABCB6) Golgi apparatus (ABCB6)
ATPase activity (ABCB6) plasma membrane (ABCB6) transmembrane transport (ABCB6)
Anatomy Link Frequency
pancreas 2
ABCB6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 2 100.00 Very High Very High Very High
fibrosis 1 65.16 Quite High
Bioavailability 8 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
antidepressant 1 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
Calcium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 3 100.00 Very High Very High Very High
Cancer 12 90.24 High High
Breast Cancer 2 81.52 Quite High
Hypoglycemia 1 74.88 Quite High
Ataxia 1 72.88 Quite High
Sideroblastic Anemia 1 72.56 Quite High
Intrahepatic Cholestasis 1 71.32 Quite High
Disease 6 69.44 Quite High
Syndrome 1 68.76 Quite High
Adrenoleukodystrophy 1 66.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BACKGROUND AND AIMS: The expression of the ABC-transporters MDR-1, MRP1, and MRP-2 was investigated in healthy pancreas and in chronic pancreatitis tissue samples in rats and humans to evaluate their possible involvement in a multidrug resistance of the pancreas with consequences for the pharmacologic treatment of pancreatic diseases.
Spec (possible) Regulation (evaluate) of Gene_expression (expression) of ABC in pancreas associated with pancreatitis and chronic pancreatitis
1) Confidence 0.44 Published 2004 Journal Pancreas Section Abstract Doc Link 14707729 Disease Relevance 0.27 Pain Relevance 0.17
Functions of ABC transporters
Regulation (Functions) of Gene_expression (transporters) of ABC
2) Confidence 0.06 Published 2005 Journal Cancer Cell Int Section Body Doc Link PMC1277830 Disease Relevance 0.93 Pain Relevance 0.03

General Comments

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