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Context Info
Confidence 0.44
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0.23

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small molecule metabolic process (CYP3A7, CYP3A4) endoplasmic reticulum (CYP3A7, CYP3A4) oxidoreductase activity (CYP3A4)
enzyme binding (CYP3A4) lipid metabolic process (CYP3A4) cytoplasm (CYP3A4)
CYP3A7 (Homo sapiens)
CYP3A4 (Homo sapiens)
Pain Link Frequency Relevance Heat
lidocaine 2 98.20 Very High Very High Very High
epidural 3 76.20 Quite High
Inflammation 1 50.20 Quite High
sodium channel 1 28.88 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 1 50.20 Quite High
Myocardial Infarction 1 37.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CYP3A4 is not mature at birth but is partly replaced by CYP3A7.
CYP3A7 Binding (replaced) of CYP3A4
1) Confidence 0.44 Published 2004 Journal Clin Pharmacokinet Section Abstract Doc Link 14715049 Disease Relevance 0.05 Pain Relevance 0.23

General Comments

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