INT115757

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Context Info
Confidence 0.57
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.53
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ABR) plasma membrane (ABR)
Anatomy Link Frequency
neurons 1
ABR (Homo sapiens)
Pain Link Frequency Relevance Heat
Neurotransmitter 2 98.64 Very High Very High Very High
Enkephalin 8 94.20 High High
medulla 8 77.92 Quite High
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 4 95.68 Very High Very High Very High
Heart Rate Under Development 2 64.88 Quite High
Hypertension 4 64.36 Quite High
Hearing Impairment 6 5.00 Very Low Very Low Very Low
Sensorineural Hearing Loss 1 5.00 Very Low Very Low Very Low
Neuropathic Pain 1 5.00 Very Low Very Low Very Low
Conductive Hearing Loss 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, if the present results hold true for humans, one can expect abnormal neurotransmitter/neuromodulator responses to environmental insults in patients with impaired ABR function.
Negative_regulation (impaired) of ABR associated with neurotransmitter
1) Confidence 0.57 Published 2004 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 14716211 Disease Relevance 0.16 Pain Relevance 0.38
These data indicate that a long-term impairment of ABR leads to chronic activation of central noradrenergic neurons and tissue renin-angiotensin system, and that stress induces exaggerated responses of neuro-humoral factors and hemodynamics in SAD rats.
Negative_regulation (impairment) of ABR in neurons associated with stress
2) Confidence 0.42 Published 2004 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 14716211 Disease Relevance 0.37 Pain Relevance 0.43
2) results in decreased ABR latency intervals with increasing age.
Negative_regulation (decreased) of ABR
3) Confidence 0.28 Published 2010 Journal Eur Arch Otorhinolaryngol Section Body Doc Link PMC2924505 Disease Relevance 0 Pain Relevance 0

General Comments

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