INT115772

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Context Info
Confidence 0.46
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ptgs2) oxidoreductase activity (Ptgs2) endoplasmic reticulum (Ptgs2)
nucleus (Ptgs2) enzyme binding (Ptgs2) protein complex (Ptgs2)
Anatomy Link Frequency
alveolar macrophages 2
Ptgs2 (Mus musculus)
Pain Link Frequency Relevance Heat
Antinociceptive 2 91.60 High High
Inflammation 2 88.88 High High
Freund adjuvant 1 87.24 High High
Hyperalgesia 1 85.96 High High
IPN 1 84.44 Quite High
Pain 2 69.92 Quite High
tail-flick 1 67.92 Quite High
Analgesic 2 64.16 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Convulsion 2 93.92 High High
INFLAMMATION 2 88.88 High High
Hyperalgesia 1 85.96 High High
Inflammatory Pain 1 84.44 Quite High
Pain 1 69.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, in primary cultures of rat alveolar macrophages, HN and compounds 1, 2, 6, and 7 (10(-8) M) significantly blocked lipopolysaccharide-induced cyclooxygenase-2 induction and prostaglandin E(2) secretion.
Positive_regulation (induced) of Localization (secretion) of cyclooxygenase-2 in alveolar macrophages
1) Confidence 0.46 Published 2004 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 14718586 Disease Relevance 0.50 Pain Relevance 0.55

General Comments

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