INT115789

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Context Info
Confidence 0.38
First Reported 2003
Last Reported 2003
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (P2rx6)
Anatomy Link Frequency
peripheral neurons 2
P2rx6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Analgesic 1 94.52 High High
Root ganglion neuron 1 75.00 Quite High
dorsal root ganglion 3 61.32 Quite High
Peripheral nervous system 1 49.40 Quite Low
adenocard 1 45.48 Quite Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 4 75.00 Quite High
Nociception 1 53.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ionized form is likely to be responsible for the suppression of the P2X3 receptor current, which may result in a reduction of the excitability of central and peripheral neurons and may contribute to the anesthetic and analgesic actions of the agent.
Spec (likely) Positive_regulation (responsible) of Negative_regulation (suppression) of P2X3 receptor in peripheral neurons associated with analgesic
1) Confidence 0.38 Published 2003 Journal Can. J. Physiol. Pharmacol. Section Abstract Doc Link 14719026 Disease Relevance 0.31 Pain Relevance 0.22

General Comments

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