INT115804

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Context Info
Confidence 0.33
First Reported 2004
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.12
Pain Relevance 1.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (OPRM1) endoplasmic reticulum (OPRM1) plasma membrane (OPRM1)
signal transducer activity (OPRM1)
Anatomy Link Frequency
plasma 2
OPRM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 229 100.00 Very High Very High Very High
agonist 20 97.04 Very High Very High Very High
alcohol 5 92.80 High High
Enkephalin 8 89.76 High High
antagonist 48 83.52 Quite High
Opioid 28 50.00 Quite Low
analgesia 20 50.00 Quite Low
narcan 11 45.72 Quite Low
Morphine 4 36.24 Quite Low
Analgesic 16 33.84 Quite Low
Disease Link Frequency Relevance Heat
Pheochromocytoma 13 63.52 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

32 43.88 Quite Low
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

15 5.00 Very Low Very Low Very Low
Pain 11 5.00 Very Low Very Low Very Low
Nociception 7 5.00 Very Low Very Low Very Low
Alcohol Addiction 6 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Recurrence 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of 20 mM ethanol on the mobility of MOP and the plasma membrane lipid dynamics were comparable to the effect of 10 mM methyl-?
Regulation (effect) of Localization (mobility) of MOP in plasma associated with opioid receptor
1) Confidence 0.33 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2602977 Disease Relevance 0.12 Pain Relevance 0.20
In this study, we determined the effect of PLD2 activity on the desensitization and resensitization rate of the mu-opioid receptor.
Spec (determined) Regulation (effect) of Localization (rate) of mu-opioid receptor associated with opioid receptor
2) Confidence 0.24 Published 2004 Journal J. Neurochem. Section Abstract Doc Link 14720217 Disease Relevance 0 Pain Relevance 0.57
Effect of H2S on MOR internalization
Regulation (Effect) of Localization (internalization) of MOR associated with opioid receptor
3) Confidence 0.08 Published 2010 Journal Mol Pain Section Body Doc Link PMC2908066 Disease Relevance 0 Pain Relevance 0.55

General Comments

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