INT115821

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Context Info
Confidence 0.33
First Reported 2003
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.51
Pain Relevance 1.02

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mitochondrion (Por) oxidoreductase activity (Por) endoplasmic reticulum (Por)
enzyme binding (Por)
Anatomy Link Frequency
liver 1
Por (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 12 99.24 Very High Very High Very High
isoflurane 3 95.76 Very High Very High Very High
Disease Link Frequency Relevance Heat
Injury 4 90.24 High High
Cancer 1 89.92 High High
Necrosis 1 89.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At 72 h of FFx, liver tissues were isolated to determine the mRNA and protein expression of CYP isozymes and NADPH-P450 reductase by reverse transcription-polymerase chain reaction and Western immunoblotting, respectively.
Spec (determine) Transcription (expression) of NADPH-P450 reductase in liver
1) Confidence 0.33 Published 2003 Journal Arch. Pharm. Res. Section Abstract Doc Link 14723344 Disease Relevance 0.51 Pain Relevance 0.09
The mRNA expression ratios of eight genes encoding DMEs that showed the greatest alterations in the previous study, namely Cyp7a1, Cyp2b15, Por, Nr1i2, Ces2, Ugt1a7, Abcb1a and Abcc2, were measured by quantitative real-time reverse transcriptase-polymerase chain reaction.
Transcription (expression) of Por
2) Confidence 0.17 Published 2009 Journal Biomed. Res. Section Abstract Doc Link 19265259 Disease Relevance 0 Pain Relevance 0.93

General Comments

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