INT115822

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Context Info
Confidence 0.35
First Reported 2003
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.96
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tnf) extracellular space (Tnf) extracellular region (Tnf)
plasma membrane (Tnf) intracellular (Tnf) extracellular matrix organization (Tnf)
Anatomy Link Frequency
paw 2
Tnf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 7 100.00 Very High Very High Very High
Inflammation 2 99.92 Very High Very High Very High
cytokine 3 93.72 High High
Pain threshold 2 92.44 High High
anesthesia 2 84.24 Quite High
glial activation 1 29.52 Quite Low
Hyperalgesia 2 27.36 Quite Low
IPN 2 22.40 Low Low
Disease Link Frequency Relevance Heat
Pain 9 100.00 Very High Very High Very High
Cancer 4 100.00 Very High Very High Very High
Necrosis 4 100.00 Very High Very High Very High
Injury 8 83.56 Quite High
Hyperalgesia 2 27.36 Quite Low
Inflammatory Pain 2 22.40 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, the mRNA levels of tumor necrosis factor-alpha (TNF-alpha), inducible nitric oxide synthase (iNOS) and heme oxygenase-1 (HO-1) were evaluated.
Regulation (evaluated) of Transcription (levels) of tumor necrosis factor-alpha associated with necrosis and cancer
1) Confidence 0.35 Published 2003 Journal Arch. Pharm. Res. Section Abstract Doc Link 14723344 Disease Relevance 0.51 Pain Relevance 0.08
In addition, the mRNA levels of tumor necrosis factor-alpha (TNF-alpha), inducible nitric oxide synthase (iNOS) and heme oxygenase-1 (HO-1) were evaluated.
Regulation (evaluated) of Transcription (levels) of TNF-alpha associated with necrosis and cancer
2) Confidence 0.35 Published 2003 Journal Arch. Pharm. Res. Section Abstract Doc Link 14723344 Disease Relevance 0.51 Pain Relevance 0.08
The effects of local pentoxifylline and propentofylline treatment on formalin-induced pain and tumor necrosis factor-alpha messenger RNA levels in the inflamed tissue of the rat paw.
Regulation (effects) of Transcription (levels) of tumor necrosis factor-alpha in paw associated with pain, necrosis, inflammation and cancer
3) Confidence 0.26 Published 2004 Journal Anesth. Analg. Section Title Doc Link 15155307 Disease Relevance 0.94 Pain Relevance 0.71

General Comments

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