INT115825

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Context Info
Confidence 0.22
First Reported 2003
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.47
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Por) oxidoreductase activity (Por) endoplasmic reticulum (Por)
enzyme binding (Por)
Por (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 1 65.12 Quite High
Angina 1 55.88 Quite High
Disease Link Frequency Relevance Heat
Necrosis 1 81.84 Quite High
Cancer 1 81.48 Quite High
Injury 4 75.00 Quite High
Cv General 3 Under Development 1 55.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The gene expression of NADPH-P450 reductase was unchanged by FFx.
Neg (unchanged) Positive_regulation (unchanged) of Gene_expression (expression) of NADPH-P450 reductase
1) Confidence 0.22 Published 2003 Journal Arch. Pharm. Res. Section Abstract Doc Link 14723344 Disease Relevance 0.42 Pain Relevance 0.07
To determine whether overexpression of NADPH cytochrome P450 reductase might act in concert with MGST1 to generate activators of sGC, we assessed GTN-induced cGMP accumulation in MGST1-overexpressing cells that had been transiently transfected with CPR.
Positive_regulation (overexpression) of Gene_expression (overexpression) of NADPH cytochrome P450 reductase
2) Confidence 0.05 Published 2009 Journal Biochem. Pharmacol. Section Abstract Doc Link 19428324 Disease Relevance 0.06 Pain Relevance 0.06

General Comments

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