INT115834

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Context Info
Confidence 0.38
First Reported 2003
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.64
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Cyp1a1) mitochondrion (Cyp1a1) oxidoreductase activity (Cyp1a1)
aging (Cyp1a1) endoplasmic reticulum (Cyp1a1) enzyme binding (Cyp1a1)
Cyp1a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 1 78.72 Quite High
cINOD 2 63.96 Quite High
Inflammation 1 63.48 Quite High
Disease Link Frequency Relevance Heat
Necrosis 1 95.44 Very High Very High Very High
Cancer 1 95.08 Very High Very High Very High
Liver Cancer 1 86.08 High High
Injury 4 78.04 Quite High
INFLAMMATION 1 63.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
FFx increased the mRNA level of CYP1A1; an increase that was not prevented by GdCl3.
Positive_regulation (increased) of Transcription (level) of CYP1A1
1) Confidence 0.38 Published 2003 Journal Arch. Pharm. Res. Section Abstract Doc Link 14723344 Disease Relevance 0.49 Pain Relevance 0.08
Sulindac induced the transcription of the CYP1A1 gene, as measured by the level of heterogeneous nuclear 1A1 RNA and by actinomycin D chase experiment.
Positive_regulation (induced) of Transcription (transcription) of CYP1A1
2) Confidence 0.34 Published 2006 Journal Carcinogenesis Section Abstract Doc Link 16531450 Disease Relevance 0.15 Pain Relevance 0.16

General Comments

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