INT115854

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Context Info
Confidence 0.53
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 0.89
Pain Relevance 1.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Trpv2) plasma membrane (Trpv2) intracellular (Trpv2)
transmembrane transport (Trpv2) cytoplasm (Trpv2)
Anatomy Link Frequency
gut 2
ganglia 1
Trpv2 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 4 94.64 High High
TRP channel 12 93.56 High High
agonist 19 89.92 High High
qutenza 12 89.24 High High
trigeminal ganglion 1 76.88 Quite High
member 8 2 76.08 Quite High
antagonist 22 5.00 Very Low Very Low Very Low
Lasting pain 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 22 90.56 High High
Ganglion Cysts 6 82.32 Quite High
Overactive Bladder 30 80.52 Quite High
Benign Prostatic Hypertrophy 2 8.48 Low Low
Fever 4 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low
Hyperalgesia 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Incontinence 2 5.00 Very Low Very Low Very Low
Urinary Dysfunction 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, RT-PCR of single nodose cell bodies, which had been retrogradely labeled from the upper gut, detected transcripts for TRPV1, TRPV2, TRPV4, TRPN1, and TRPM8 in a proportion of cells.
Transcription (detected) of TRPV2 in gut
1) Confidence 0.53 Published 2004 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 14726308 Disease Relevance 0.16 Pain Relevance 0.34
TRPV1, TRPV2, TRPV3 and TRPV4 mRNAs were expressed in spiral and vestibular ganglia, and TRPV2 and TRPV1 mRNAs were most predominant in control mice.
Transcription (expressed) of TRPV2 in ganglia
2) Confidence 0.51 Published 2005 Journal Hear. Res. Section Abstract Doc Link 15721568 Disease Relevance 0.08 Pain Relevance 0.23
In addition, RT-PCR of single nodose cell bodies, which had been retrogradely labeled from the upper gut, detected transcripts for TRPV1, TRPV2, TRPV4, TRPN1, and TRPM8 in a proportion of cells.
Transcription (transcripts) of TRPV2 in gut
3) Confidence 0.39 Published 2004 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 14726308 Disease Relevance 0.16 Pain Relevance 0.34
Quantitative polymerase chain reaction showed very low levels of TRPA1 and TRPV1 mRNA but high levels of TRPV4 and TRPV2 mRNA.
Transcription (levels) of TRPV2
4) Confidence 0.38 Published 2010 Journal F1000 Biol Rep Section Body Doc Link PMC2948364 Disease Relevance 0.25 Pain Relevance 0.13
Quantitative polymerase chain reaction showed very low levels of TRPA1 and TRPV1 mRNA but high levels of TRPV4 and TRPV2 mRNA.
Transcription (levels) of TRPV2
5) Confidence 0.28 Published 2010 Journal F1000 Biol Rep Section Body Doc Link PMC2948364 Disease Relevance 0.24 Pain Relevance 0.13

General Comments

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