INT115915

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Context Info
Confidence 0.06
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.36
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

immune system process (AHR) small molecule metabolic process (CYP2B6) cell morphogenesis (AHR)
endoplasmic reticulum (CYP2B6) DNA binding (AHR) response to stress (AHR)
Anatomy Link Frequency
1A2 4
AHR (Homo sapiens)
CYP2B6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Analgesic 4 81.76 Quite High
antagonist 2 75.00 Quite High
aspirin 6 74.00 Quite High
Disease Link Frequency Relevance Heat
Cancer 2 96.48 Very High Very High Very High
Hepatocellular Cancer 2 85.36 High High
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The detrimental effects of TCDD are mediated via the aryl hydrocarbon receptor (AhR), a transcription factor that regulates the expression of the carcinogen-activating enzymes cytochromes P-450 (CYP) 1A1, 1A2, and 1B1.
AhR Regulation (regulates) of Gene_expression (expression) of cytochromes P-450 in 1A2
1) Confidence 0.06 Published 2004 Journal Cancer Res. Section Abstract Doc Link 14729655 Disease Relevance 0.18 Pain Relevance 0.22
The detrimental effects of TCDD are mediated via the aryl hydrocarbon receptor (AhR), a transcription factor that regulates the expression of the carcinogen-activating enzymes cytochromes P-450 (CYP) 1A1, 1A2, and 1B1.
aryl hydrocarbon receptor Regulation (regulates) of Gene_expression (expression) of cytochromes P-450 in 1A2
2) Confidence 0.06 Published 2004 Journal Cancer Res. Section Abstract Doc Link 14729655 Disease Relevance 0.18 Pain Relevance 0.22

General Comments

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