INT116081

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Context Info
Confidence 0.41
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ARRB1) plasma membrane (ARRB1) nucleus (ARRB1)
transcription factor binding (ARRB1) cytoplasm (ARRB1)
ARRB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Delta opioid receptors 4 99.36 Very High Very High Very High
opioid receptor 3 99.24 Very High Very High Very High
Morphine 5 92.68 High High
Opioid 2 83.16 Quite High
Kinase C 1 78.24 Quite High
Immobilon 3 74.20 Quite High
Glutamate 1 69.00 Quite High
agonist 1 34.12 Quite Low
opiate 1 33.76 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that ERK/MAP kinase activity prevents opioid receptor desensitization and sequestration by blocking arrestin 2 interaction with activated DORs.
Negative_regulation (blocking) of arrestin 2 Binding (interaction) of associated with delta opioid receptors and opioid receptor
1) Confidence 0.41 Published 2004 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 14742744 Disease Relevance 0 Pain Relevance 0.72

General Comments

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