INT116094

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Context Info
Confidence 0.06
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (TFF2) plasma membrane (TACR1) cytoplasm (TACR1)
signal transducer activity (TACR1)
TACR1 (Homo sapiens)
TFF2 (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 11 100.00 Very High Very High Very High
opioid receptor 7 99.96 Very High Very High Very High
Morphine 8 99.58 Very High Very High Very High
Central nervous system 1 87.20 High High
antagonist 4 79.16 Quite High
agonist 1 66.92 Quite High
chemokine 1 47.68 Quite Low
cytokine 1 47.08 Quite Low
Inflammation 1 46.68 Quite Low
Neuropeptide 1 44.40 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 1 46.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that morphine, by activating MOR, engages a positive feedback loop between NK-1R and SP.
NK-1R Binding (engages) of SP associated with opioid receptor, substance p and morphine
1) Confidence 0.06 Published 2004 Journal J. Neurosci. Res. Section Abstract Doc Link 14743438 Disease Relevance 0 Pain Relevance 1.47

General Comments

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