INT116114

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.12
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 3.99
Pain Relevance 1.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (EID1) nucleus (EID1) cell cycle (EID1)
cytoplasm (EID1)
EID1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 8 99.84 Very High Very High Very High
corticosteroid 2 98.96 Very High Very High Very High
qutenza 11 97.28 Very High Very High Very High
Pyramidal cell 52 95.60 Very High Very High Very High
aspirin 3 89.12 High High
Enkephalin 1 80.00 Quite High
Inflammation 20 79.48 Quite High
Opioid 2 78.40 Quite High
Inflammatory stimuli 2 71.68 Quite High
narcan 1 70.56 Quite High
Disease Link Frequency Relevance Heat
Retinoblastoma 10 100.00 Very High Very High Very High
Apoptosis 13 99.50 Very High Very High Very High
Disease 83 97.44 Very High Very High Very High
Congenital Anomalies 3 92.56 High High
Cancer 99 89.84 High High
Obesity 140 86.60 High High
Tauopathy 80 81.88 Quite High
INFLAMMATION 24 79.48 Quite High
Pancreatic Cancer 15 79.28 Quite High
Head & Neck Cancer 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using SCC-1 cells, OGF decreased the phosphorylation of retinoblastoma protein.
Phosphorylation (phosphorylation) of retinoblastoma protein associated with retinoblastoma
1) Confidence 0.12 Published 2007 Journal Cancer Res. Section Abstract Doc Link 17974995 Disease Relevance 0.25 Pain Relevance 0.27
The inhibition of cyclin D1-CDK4/6 complex activity prevents retinoblastoma protein phosphorylation and release of E2F, leading to the inhibition of cell cycle in G1/S transition [3].
Phosphorylation (phosphorylation) of retinoblastoma protein associated with retinoblastoma
2) Confidence 0.07 Published 2005 Journal BMC Gastroenterol Section Body Doc Link PMC1185532 Disease Relevance 1.01 Pain Relevance 0
This effect correlated with the down-regulation of the expression of cyclin D1 that led to inhibition of cyclin-dependent kinase 4-mediated phosphorylation of retinoblastoma protein.
Phosphorylation (phosphorylation) of retinoblastoma protein associated with retinoblastoma
3) Confidence 0.05 Published 2004 Journal Cancer Res. Section Abstract Doc Link 14744780 Disease Relevance 0.31 Pain Relevance 0.85
Moreover, because of its biological effects, that is, inhibition of p53-induced apoptosis [28] and suppression of phosphorylation of the retinoblastoma protein [29], its drop might contribute to the favorable course of the disease.
Phosphorylation (phosphorylation) of retinoblastoma protein associated with disease, retinoblastoma and apoptosis
4) Confidence 0.02 Published 2010 Journal Clinical and Developmental Immunology Section Body Doc Link PMC3004381 Disease Relevance 0.67 Pain Relevance 0
to hypophosphorylated retinoblastoma protein (RB) and histone deacetylase 3 (HDAC3) [18].
Phosphorylation (hypophosphorylated) of retinoblastoma protein associated with retinoblastoma
5) Confidence 0.01 Published 2009 Journal PPAR Research Section Body Doc Link PMC2830574 Disease Relevance 0.33 Pain Relevance 0.08
Cyclins D1, D2, D3 with cdk4 and cdk6, regulate G1/S transition by releasing E2F transcription factors via increased phosphorylation of retinoblastoma protein.
Phosphorylation (phosphorylation) of retinoblastoma protein associated with retinoblastoma
6) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2748684 Disease Relevance 0.53 Pain Relevance 0.08
PCNA and phosphorylated retinoblastoma protein (Figure 8A).
Phosphorylation (phosphorylated) of retinoblastoma protein associated with retinoblastoma
7) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2748684 Disease Relevance 0.31 Pain Relevance 0.03
B activation can therefore reduce cyclin D1 activity and subsequent phosphorylation of the retinoblastoma protein.
Phosphorylation (phosphorylation) of retinoblastoma protein associated with retinoblastoma
8) Confidence 0.01 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2745153 Disease Relevance 0.57 Pain Relevance 0.44

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox