INT116119

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Context Info
Confidence 0.75
First Reported 2004
Last Reported 2004
Negated 2
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 3.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Nfx1) DNA binding (Nfx1) cellular_component (Nfx1)
ligase activity (Nfx1)
Anatomy Link Frequency
urine 1
Nfx1 (Mus musculus)
Pain Link Frequency Relevance Heat
fluoxetine 51 100.00 Very High Very High Very High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There was also no fetal production of FX and NFX glucuronides in vivo.
Neg (no) Gene_expression (production) of NFX associated with fluoxetine
1) Confidence 0.75 Published 2004 Journal Drug Metab. Dispos. Section Abstract Doc Link 14744943 Disease Relevance 0 Pain Relevance 1.31
In contrast, NFX was not detected in the fetus after fetal FX administration, which is consistent with the absence of measurable fetal nonplacental clearance of the drug and the lack of NFX formation in fetal hepatic microsomal incubations.
Neg (not) Gene_expression (detected) of NFX associated with fluoxetine
2) Confidence 0.75 Published 2004 Journal Drug Metab. Dispos. Section Abstract Doc Link 14744943 Disease Relevance 0 Pain Relevance 1.23
FX, NFX, and their glucuronides were present in maternal urine but accounted for only 3.4% of maternal drug elimination.
Gene_expression (present) of NFX in urine associated with fluoxetine
3) Confidence 0.57 Published 2004 Journal Drug Metab. Dispos. Section Abstract Doc Link 14744943 Disease Relevance 0 Pain Relevance 1.18

General Comments

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