INT116145

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Context Info
Confidence 0.27
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.68
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tnfrsf21) cytoplasm (Tnfrsf21)
Anatomy Link Frequency
parenchymal cells 1
Tnfrsf21 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 16 99.70 Very High Very High Very High
adenocard 1 47.12 Quite Low
Disease Link Frequency Relevance Heat
Death 5 100.00 Very High Very High Very High
Infection 1 99.96 Very High Very High Very High
Viral Infection 2 98.96 Very High Very High Very High
Apoptosis 6 96.88 Very High Very High Very High
Hepatotoxicity 4 96.76 Very High Very High Very High
Nephrotoxicity 2 93.76 High High
Injury 2 90.00 High High
Chronic Renal Failure 1 88.08 High High
Stress 3 75.00 Quite High
Necrosis 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
During such infections, death receptor ligands are expressed at low levels, and most parenchymal cells survive.
Gene_expression (expressed) of death receptor in parenchymal cells associated with death and infection
1) Confidence 0.27 Published 2004 Journal Hepatology Section Abstract Doc Link 14999684 Disease Relevance 0.65 Pain Relevance 0.14
While paracetamol increased the expression of the death receptor Fas on the cell surface, the Fas pathway was not involved in the paracetamol-induced apoptosis of tubular cells.
Gene_expression (expression) of death receptor associated with paracetamol, apoptosis and death
2) Confidence 0.17 Published 2004 Journal J. Am. Soc. Nephrol. Section Abstract Doc Link 14747384 Disease Relevance 1.02 Pain Relevance 0.79

General Comments

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