INT116248

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Context Info
Confidence 0.49
First Reported 2004
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.28
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IAPP) extracellular region (IAPP) cell-cell signaling (IAPP)
Anatomy Link Frequency
blood 2
IAPP (Homo sapiens)
Pain Link Frequency Relevance Heat
Cholecystokinin 1 100.00 Very High Very High Very High
Opioid 1 100.00 Very High Very High Very High
Neuropeptide 10 99.80 Very High Very High Very High
Central nervous system 1 72.80 Quite High
Calcitonin gene-related peptide 1 72.00 Quite High
qutenza 1 67.92 Quite High
noradrenaline 1 25.96 Quite Low
cva 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 1 86.40 High High
Ulcers 1 81.32 Quite High
Disorders Of Creatine Metabolism 15 58.72 Quite High
Hypertension 3 56.96 Quite High
Cirrhosis 29 50.00 Quite Low
Pressure And Volume Under Development 14 50.00 Quite Low
Critical Illness 2 50.00 Quite Low
Hepatorenal Syndrome 1 50.00 Quite Low
Syndrome 23 24.36 Low Low
Renal Failure 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Centrally and /or peripherally injected neuropeptides, such as amylin, adrenomedullin, bombesin, cholecystokinin, neurotensin, opioid peptides, thyreotropin releasing hormone and vasoactive intestinal peptide, influence both the acid secretion and the gastric mucosal lesions induced by different ulcerogens.
Positive_regulation (induced) of Localization (secretion) of amylin associated with neuropeptide, opioid and cholecystokinin
1) Confidence 0.49 Published 2004 Journal Curr Top Med Chem Section Abstract Doc Link 14754377 Disease Relevance 0.17 Pain Relevance 0.62
On the other hand, release of IAP may increase splanchnic blood flow at lower pressures [22].
Spec (may) Positive_regulation (increase) of Localization (release) of IAP in blood
2) Confidence 0.29 Published 2008 Journal Crit Care Section Body Doc Link PMC2374626 Disease Relevance 0.12 Pain Relevance 0

General Comments

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