INT116512

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Context Info
Confidence 0.75
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.61
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MVD) small molecule metabolic process (MVD) lyase activity (MVD)
peroxisome (MVD) kinase activity (MVD)
MVD (Homo sapiens)
Pain Link Frequency Relevance Heat
Ventral tegmentum 37 98.60 Very High Very High Very High
Nucleus accumbens 36 98.40 Very High Very High Very High
Dopamine 30 92.24 High High
antagonist 1 67.60 Quite High
dexamethasone 5 63.40 Quite High
endometriosis 2 50.00 Quite Low
Central nervous system 6 22.64 Low Low
Eae 13 16.96 Low Low
Dismenorea 1 10.00 Low Low
COX2 1 10.00 Low Low
Disease Link Frequency Relevance Heat
Myeloproliferative Disorder 12 99.84 Very High Very High Very High
Myelofibrosis 10 91.80 High High
Myelodysplastic Syndromes 18 91.28 High High
Endometriosis (extended) 2 78.88 Quite High
Reprotox - General 3 1 77.32 Quite High
Colon Cancer 3 67.48 Quite High
Cognitive Disorder 5 65.44 Quite High
Cancer 25 65.16 Quite High
Multiple Myeloma 24 64.68 Quite High
INFLAMMATION 1 64.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MVD and VEGF expression in the treated tumor tissue declined noticeably as compared with the controls.
Gene_expression (expression) of MVD
1) Confidence 0.75 Published 2004 Journal Di Yi Jun Yi Da Xue Xue Bao Section Body Doc Link 14965822 Disease Relevance 0.20 Pain Relevance 0
Immunohistochemical staining for CD34 and vascular endothelial growth factor (VEGF) in histological specimens for MVD and VEGF cellular expression assessment were performed.
Gene_expression (expression) of MVD
2) Confidence 0.75 Published 2008 Journal J Womens Health (Larchmt) Section Body Doc Link 18479230 Disease Relevance 0.16 Pain Relevance 0
In a recent study [30], we found a significantly increased MVD and VEGF expression in MPN compared to controls, particularly in cases with high JAK2-V617F mutant allele burdens.
Gene_expression (expression) of MVD associated with myeloproliferative disorder
3) Confidence 0.58 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2875768 Disease Relevance 1.19 Pain Relevance 0.09
This may lead to a plausible explanation for the differences in the MPD-induced attenuation of N2 and P3 amplitudes among the VTA, NAc, and PFC (Fig. 5).
Gene_expression (attenuation) of MPD-induced associated with nucleus accumbens and ventral tegmentum
4) Confidence 0.19 Published 2006 Journal Behav Brain Funct Section Body Doc Link PMC1360669 Disease Relevance 0.07 Pain Relevance 0.97

General Comments

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