INT116653

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Context Info
Confidence 0.28
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.59
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Eras) plasma membrane (Eras) GTPase activity (Eras)
cellular_component (Eras) biological_process (Eras)
Eras (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 20 100.00 Very High Very High Very High
aspirin 7 92.28 High High
Potency 4 80.32 Quite High
cINOD 1 75.12 Quite High
Pain 6 70.96 Quite High
headache 4 59.00 Quite High
nud 2 58.20 Quite High
tetrodotoxin 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Action potential 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Hypertension 36 99.92 Very High Very High Very High
Stress 4 97.32 Very High Very High Very High
Pressure And Volume Under Development 4 90.88 High High
Colon Cancer 16 84.52 Quite High
Cancer 1 82.96 Quite High
INFLAMMATION 1 74.88 Quite High
Pain 6 70.96 Quite High
Aging 1 68.84 Quite High
Severe Combined Immunodeficiency 1 65.36 Quite High
Teratoma 2 62.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients assigned to cohort 2 and 3 with ERAS recovery will receive additional information about the ERAS program by an ERAS nurse and an anesthesiologist prior to hospital admittance.
Gene_expression (program) of ERAS
1) Confidence 0.28 Published 2010 Journal BMC Surg Section Body Doc Link PMC2901198 Disease Relevance 0.11 Pain Relevance 0
We evaluated the expression of Oct4 (POU5F1) to determine whether exogenic Oct4 induced the expression of early developmental genes KLF4, Sox-2, Rex-1, Utf1, Dapp5, FGF4, ERas, and Nanog in cultured ATSCs (Fig. 1E).
Gene_expression (expression) of ERas
2) Confidence 0.27 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2747014 Disease Relevance 0.25 Pain Relevance 0.04
The small GTPase Rac1 is highly induced and this was confirmed by immunoblotting.
Gene_expression (induced) of small GTPase
3) Confidence 0.16 Published 2004 Journal Carcinogenesis Section Abstract Doc Link 14976132 Disease Relevance 0.49 Pain Relevance 0.31
Prostanoids, ERAs, and PDE5 inhibitors provide symptomatic relief and improve the functional as well as hemodynamic status of patients with PAH.
Gene_expression (Prostanoids) of ERAs associated with pulmonary hypertension and antagonist
4) Confidence 0.14 Published 2010 Journal Respir Res Section Body Doc Link PMC2835653 Disease Relevance 0.73 Pain Relevance 0.30

General Comments

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