INT116676

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Context Info
Confidence 0.53
First Reported 2003
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.33
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ADRBK1) signal transduction (ADRBK1) aging (ADRBK1)
plasma membrane (ADRBK1) cytoplasm (ADRBK1)
ADRBK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 59 94.32 High High
Dismenorea 1 81.20 Quite High
antagonist 3 20.76 Low Low
Kinase C 18 5.00 Very Low Very Low Very Low
Inflammation 11 5.00 Very Low Very Low Very Low
bradykinin 10 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
adenocard 8 5.00 Very Low Very Low Very Low
Catecholamine 3 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 43 82.68 Quite High
Dysmenorrhea 1 81.20 Quite High
Disease 10 80.56 Quite High
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Occupational Lung Diseases 9 5.00 Very Low Very Low Very Low
Bronchospasm 2 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Airway Remodeling 2 5.00 Very Low Very Low Very Low
Bordatella Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GRK2/receptor interactions started within 4 sec, peaked at 10 sec, and decreased to less than 40% within 8 min.
Negative_regulation (decreased) of GRK2 Binding (interactions) of
1) Confidence 0.53 Published 2004 Journal Mol. Endocrinol. Section Abstract Doc Link 14976224 Disease Relevance 0.08 Pain Relevance 0.17
Interestingly, GRK2 has been recently shown to contain an RGS domain that can interact specifically with G?
Negative_regulation (recently) of GRK2 Binding (shown) of
2) Confidence 0.10 Published 2003 Journal Respir Res Section Body Doc Link PMC152647 Disease Relevance 0.25 Pain Relevance 0.06

General Comments

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