INT116724

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.41
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 7
Disease Relevance 7.92
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (CETP) transport (CETP) extracellular space (CETP)
small molecule metabolic process (CETP) extracellular region (CETP) lipid metabolic process (CETP)
Anatomy Link Frequency
adipose tissue 4
plasma 2
liver 1
spleen 1
CETP (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 20 96.44 Very High Very High Very High
agonist 75 20.40 Low Low
alcohol 55 5.00 Very Low Very Low Very Low
Inflammation 45 5.00 Very Low Very Low Very Low
Angina 18 5.00 Very Low Very Low Very Low
ischemia 10 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
Nicotine 5 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
Potency 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 1521 100.00 Very High Very High Very High
Obesity 5 99.96 Very High Very High Very High
Targeted Disruption 67 99.88 Very High Very High Very High
Coronary Heart Disease 165 99.36 Very High Very High Very High
Atherosclerosis 246 82.88 Quite High
Renal Failure 5 81.00 Quite High
Anaemia 5 80.28 Quite High
Disease 26 78.20 Quite High
Coronary Artery Disease 32 76.68 Quite High
Syndrome 5 72.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Clee et al. [28] have shown that, in double transgenic mice overexpressing LPL and CETP, HDL cholesterol levels were significantly influenced by the LPL activity while no such correlation was observed in the absence of CETP expression.
Positive_regulation (overexpressing) of Gene_expression (overexpressing) of CETP associated with targeted disruption and disorder of lipid metabolism
1) Confidence 0.41 Published 2001 Journal BMC Biochem Section Body Doc Link PMC31329 Disease Relevance 0.99 Pain Relevance 0
Found predominantly in the liver, spleen, and adipose tissue, expression of CETP is enhanced by hypercholesterolemic diets via activation of a sterol regulatory protein and through binding of oxysterols to the LXR/RXR receptor (De Grooth et al 2004).
Positive_regulation (enhanced) of Gene_expression (expression) of CETP in adipose tissue associated with obesity
2) Confidence 0.35 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.22 Pain Relevance 0.05
Phase three: cholesterol ester transfer protein (CETP) mediates exchange of cholesterol esters between HDL-C and Apo B lipoproteins
Positive_regulation (-) of Gene_expression (exchange) of CETP associated with disorder of lipid metabolism
3) Confidence 0.35 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.51 Pain Relevance 0.04
Phase three: cholesterol ester transfer protein (CETP) mediates exchange of cholesterol esters between HDL-C and Apo B lipoproteins
Positive_regulation (-) of Gene_expression (exchange) of cholesterol ester transfer protein associated with disorder of lipid metabolism
4) Confidence 0.35 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.53 Pain Relevance 0.04
The plasma levels of apoB, apo CIII, Ox-LDL, CETP, hs-CRP and homocysteine were equally increased in both the VSA and CAD groups.
Positive_regulation (increased) of Gene_expression (levels) of CETP in plasma
5) Confidence 0.29 Published 2003 Journal Nutr Metab Cardiovasc Dis Section Body Doc Link 14979683 Disease Relevance 0.23 Pain Relevance 0
Found predominantly in the liver, spleen, and adipose tissue, expression of CETP is enhanced by hypercholesterolemic diets via activation of a sterol regulatory protein and through binding of oxysterols to the LXR/RXR receptor (De Grooth et al 2004).
Positive_regulation (enhanced) of in spleen Gene_expression (expression) of CETP in adipose tissue associated with obesity
6) Confidence 0.12 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.22 Pain Relevance 0.05
Found predominantly in the liver, spleen, and adipose tissue, expression of CETP is enhanced by hypercholesterolemic diets via activation of a sterol regulatory protein and through binding of oxysterols to the LXR/RXR receptor (De Grooth et al 2004).
Positive_regulation (enhanced) of in liver Gene_expression (expression) of CETP in adipose tissue associated with obesity
7) Confidence 0.12 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.22 Pain Relevance 0.05

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox