INT116727

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Context Info
Confidence 0.53
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.13
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasmic membrane-bounded vesicle (Flg) cytoskeleton organization (Flg)
Anatomy Link Frequency
Bar 1
Flg (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 43 86.56 High High
Inflammatory response 10 79.60 Quite High
agonist 3 70.84 Quite High
cytokine 19 50.80 Quite High
Pain 2 25.00 Low Low
chemokine 3 5.00 Very Low Very Low Very Low
member 8 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Francisella Infection 58 100.00 Very High Very High Very High
Sprains And Strains 38 100.00 Very High Very High Very High
Ichthyosis Vulgaris 1 99.12 Very High Very High Very High
Dermatitis 6 98.20 Very High Very High Very High
Congenital Anomalies 11 91.56 High High
Disease 5 90.56 High High
Death 3 89.48 High High
INFLAMMATION 51 85.16 High High
Pruritus 1 82.88 Quite High
Ichthyosis 6 80.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Female C57BL/6J mice were obtained from Jackson Labs in Bar Harbor, ME. 48 hours prior to Ft LVS challenge, mice were injected i.p. with either 100 ng of Ft LVS LPS or an equivalent volume of saline.
Gene_expression (challenge) of Ft in Bar associated with sprains and strains and francisella infection
1) Confidence 0.53 Published 2010 Journal BMC Infect Dis Section Body Doc Link PMC2826305 Disease Relevance 2.25 Pain Relevance 0.15
In addition, the filaggrin protein was normally processed in K5-R1/R2 mice (unpublished data).
Gene_expression (processed) of filaggrin protein
2) Confidence 0.31 Published 2010 Journal The Journal of Cell Biology Section Body Doc Link PMC2845079 Disease Relevance 0.44 Pain Relevance 0.19
Ichthyosis vulgaris is probably a post-translational defect in pro-filaggrin expression.
Gene_expression (expression) of pro-filaggrin associated with ichthyosis vulgaris
3) Confidence 0.02 Published 2004 Journal Am J Clin Dermatol Section Abstract Doc Link 14979740 Disease Relevance 0.45 Pain Relevance 0

General Comments

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