INT116751

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Context Info
Confidence 0.28
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprm1, Pik3cd) cell differentiation (Pik3cd) plasma membrane (Oprm1)
kinase activity (Pik3cd) signal transducer activity (Oprm1)
Anatomy Link Frequency
gray matter 2
Oprm1 (Mus musculus)
Pik3cd (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 5 100.00 Very High Very High Very High
Pain 3 100.00 Very High Very High Very High
Central grey 2 99.44 Very High Very High Very High
Morphine 6 96.72 Very High Very High Very High
antinociception 2 96.04 Very High Very High Very High
Nerve growth factor 1 89.00 High High
agonist 1 82.68 Quite High
Antinociceptive 2 49.88 Quite Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 6 99.44 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased level of neuronal phosphoinositide 3-kinase gamma by the activation of mu-opioid receptor in the mouse periaqueductal gray matter: further evidence for the implication in morphine-induced antinociception.
Positive_regulation (activation) of mu-opioid receptor in gray matter Positive_regulation (Increased) of phosphoinositide 3-kinase associated with pain, antinociception, opioid receptor, central grey and morphine
1) Confidence 0.28 Published 2004 Journal Neuroscience Section Title Doc Link 14980723 Disease Relevance 0.38 Pain Relevance 1.01

General Comments

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