INT116777

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Context Info
Confidence 0.01
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.24
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular matrix organization (Fn1) cytoplasm (Psma5) peptidase activity (Psma5)
extracellular space (Fn1) extracellular region (Fn1) nucleolus (Psma5)
Anatomy Link Frequency
EPI 2
Psma5 (Rattus norvegicus)
Fn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hyperalgesia 8 99.48 Very High Very High Very High
intrathecal 1 81.12 Quite High
Neuropathic pain 2 77.96 Quite High
Inflammation 6 77.16 Quite High
Pain 4 74.44 Quite High
Taxol 1 56.08 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 8 99.48 Very High Very High Very High
Neuropathic Pain 4 77.96 Quite High
INFLAMMATION 4 77.16 Quite High
Adhesions 1 76.12 Quite High
Pain 1 74.44 Quite High
Cancer 1 58.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Monoclonal antibodies (mAbs) against the alpha1 or alpha3 integrin subunits, which participate in laminin binding, selectively blocked PGE2 hyperalgesia, while a mAb against the alpha5 subunit, which participates in fibronectin binding, blocked only EPI-induced hyperalgesia.
alpha5 subunit Positive_regulation (participates) of fibronectin Binding (binding) of in EPI associated with hyperalgesia
1) Confidence 0.01 Published 2004 Journal Eur. J. Neurosci. Section Abstract Doc Link 14984413 Disease Relevance 1.24 Pain Relevance 1.06

General Comments

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