INT116877

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Context Info
Confidence 0.17
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 3.41
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (LUZP4)
Anatomy Link Frequency
SCP 1
LUZP4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 10 96.24 Very High Very High Very High
Disease Link Frequency Relevance Heat
Testicular Cancer 20 100.00 Very High Very High Very High
Pancreatic Cancer 10 99.36 Very High Very High Very High
Cancer 2 99.06 Very High Very High Very High
Adenocarcinoma 4 96.88 Very High Very High Very High
Pancreatitis 10 96.24 Very High Very High Very High
Malignant Neoplastic Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In order to define antigens that might be suitable as vaccines for pancreatic carcinoma, we investigated the composite expression of 10 cancer testis (CT) antigens (SCP-1, NY-ESO-1, SSX-1, SSX-2, SSX-4, GAGE, MAGE-3, MAGE-4, CT-7 and CT-8) by Reverse Transcriptase-PCR (RT-PCR) in fresh biopsies of human pancreatic adenocarcinoma, chronic pancreatitis and pancreatic carcinoma cell lines.
Gene_expression (expression) of CT-8 in SCP associated with adenocarcinoma, pancreatic cancer, testicular cancer and chronic pancreatitis
1) Confidence 0.17 Published 2004 Journal Int. J. Cancer Section Abstract Doc Link 14991579 Disease Relevance 1.59 Pain Relevance 0.17
While all CT genes were frequently expressed in cell lines derived from pancreatic cancer, no expression of MAGE-3, SSX-1, SSX-2, NY-ESO-1 and CT-7 was detected in fresh tumor biopsies, and MAGE-4 (1/52), SSX-4 (1/39) and CT-8 (2/41) were only rarely expressed.
Gene_expression (expressed) of CT-8 associated with cancer, pancreatic cancer and testicular cancer
2) Confidence 0.12 Published 2004 Journal Int. J. Cancer Section Abstract Doc Link 14991579 Disease Relevance 1.83 Pain Relevance 0.29

General Comments

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